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These Are the Leading Cryptocurrencies With the Most Profitable Holders: Details

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TL;DR

  • Tron (TRX) leads with 87% of investors currently in profit.
  • Cardano (ADA) is on the opposite side, with most of its holders underwater.

Bitcoin (BTC) is Among the Leaders

The enhanced volatility of the cryptocurrency market has significantly affected investors in different digital assets. At the start of the week, prices were plummeting, resulting in substantial paper losses for HODLers, while the subsequent comeback partially fixed the situation for those who endured the turbulence without selling their stash.

In the following lines, we will check the percentage of profitable investors in some of the leading digital currencies (more specifically, those with a market cap of over $10 billion).

The ones invested in Tron (TRX) are leading the pack. According to IntoTheBlock, approximately 87% of the holders are in the green, while only 8% are underwater. 

Bitcoin (BTC) is next in line. Around 85% of those who have entered the ecosystem are sitting on some paper profits, whereas 13% are in the red. The majority of BTC investors (71%) have hopped on the bandwagon more than a year ago, 24% have done so in the past 12 months, while only 5% dived in the last 30 days. 

The biggest meme coin, Dogecoin (DOGE), ranks third, with 70% of its holders currently in the money on their investments. Similar to BTC, most of its investors entered the ecosystem at least a year ago.

Fourth place in terms of profitability belongs to Ethereum (ETH) which was one of the worst-affected assets during the Monday (August 5) crash. As of the moment, 68% of the holders are in the green and 28% are sitting on paper losses.

What About the Biggest Losers?

Some of the leading cryptocurrencies, on the other hand, have not been that kind to their holders. For instance, 52% of the Shiba Inu (SHIB) investors are currently underwater, while 47% are profitable. The situation was much more different during the bull run in mid-March, when approximately 63% of the holders were in the green.

Cardano (ADA) holders have fared even worse. As CryptoPotato reported amidst the market collapse on August 5, the share of investors sitting on some paper profits was under 1%. The subsequent rebound of the sector slightly changed the grim picture, and as of the moment, 16% of ADA HODLers see an increase in their initial investment.

Other well-known cryptocurrencies whose investors are predominantly in the red include Chainlink (LINK), Avalanche (AVAX), Litecoin (LTC), Dai (DAI), and more.

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Cryptocurrency

Bitcoin Price Slides to $103K as Major Altcoins Crash (Weekend Watch)

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The broader cryptocurrency market continues struggling amid mounting geopolitical and economic pressures.

Bitcoin’s price has lost almost 3% on the day, while major altcoins such as Ethereum, Solana, Cardano, and others chart even more considerable declines.

Bitcoin Price Tumbles toward $103K

Bitcoin is charting a near 3% loss in the past 24 hours in what seems to be a broader crypto market selloff.

As seen in the chart below, the price tumbled from around $106,000 to an intraday low at $102,400 before bouncing and settling at where it current trades at the time of this writing.

BTCUSD_2025-06-21_11-32-32
Source: TradingView

As CryptoPotato reported, however, the common theme amongst the majority of cryptocurrency analysts and experts is that Bitcoin’s price trading at around $100,000 is indicative of institutional dominance and not retail FOMO.

This suggests that it has much more staying power because institutions are a lot less likely to sell during temporary and sudden drawdowns like the current one.

At the same time, however, the war between Israel and Iran continues, driving oil prices up and causing turmoil on stock markets as well.

Altcoins Crash Harder than BTC

The heatmap below paints a clear picture: most of the altcoins are trading in the red and are charting consiedrable losses.

Namely, some of the larger-cap cryptocurrencies such as ETH, SOL, ADA, DOGE, HYPE, BCH, LINK, AVAX, and more, are declining for more than 3% during the past 24 hours.

Interestingly enough, Bitcoin’s dominance – the metric, which tracks its share relative to that of the rest of the market is up by more than 1% during the same period.

This shows that BTC is performing a lot better and altcoins are completely unable to capitalize on its drawdown. In fact, this seems to be the other theme of the current cycle.

Screenshot 2025-06-21 at 11.45.41
Source: Quantify Crypto
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Disclaimer: Information found on CryptoPotato is those of writers quoted. It does not represent the opinions of CryptoPotato on whether to buy, sell, or hold any investments. You are advised to conduct your own research before making any investment decisions. Use provided information at your own risk. See Disclaimer for more information.

Cryptocurrency charts by TradingView.

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Cryptocurrency

Semler Scientific Unveils Plan to Accumulate 105,000 BTC by 2027

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Nasdaq-listed healthcare technology company, Semler Scientific, has outlined a bold multi-year plan to significantly expand its Bitcoin holdings. The company aims to hold 10,000 BTC by the end of 2025 as an initial milestone. Building on this, it plans to increase its holdings to 42,000 BTC by the end of 2026.

By the close of 2027, Semler intends to reach a total of 105,000 BTC.

Semler Reports 287% Bitcoin Yield to Date

According to the official press release, the company said it will fund these purchases using a mix of equity and debt financing, as well as operational cash flows. Semler, which in May 2024 became the second US public company to adopt Bitcoin as its primary treasury reserve asset, has since emerged as a significant corporate Bitcoin holder.

As of June 3, 2025, the firm reported a 287% yield on its Bitcoin investment and a $177 million unrealized gain.

In a move to strengthen its new approach, Semler has appointed Joe Burnett as Director of Bitcoin Strategy. Burnett, formerly Director of Market Research at Unchained, brings more than seven years of experience in Bitcoin advocacy and research.

In a statement, Eric Semler, chairman of Semler Scientific, said,

“We are excited to have Joe join our Bitcoin strategy team and help drive our three-year-plan to own 105,000 Bitcoins. Joe is an analytical thought leader on Bitcoin and Bitcoin treasury companies. His expertise will be instrumental as we pursue our Bitcoin treasury strategy and aim to deliver long-term value to our stockholders.”

Corporate Bitcoin Holdings Grow

An increasing number of public companies are deepening their involvement with the largest cryptocurrency. For instance, Genius Group, an AI-driven education company, recently increased its corporate Bitcoin reserves from 66 BTC to 100 BTC, after acquiring an additional 34 BTC valued at approximately $3.42 million.

The company resumed its Bitcoin purchases on May 22, following a May 6 US Court of Appeals ruling that lifted previous legal restrictions stemming from a dispute related to its merger with FatBrain AI. CEO Roger Hamilton described reaching 100 BTC as a milestone in their broader plan to accumulate 1,000 BTC.

Earlier this month, New York-based Mercurity Fintech Holding announced it would raise $800 million to build a Bitcoin treasury reserve. The company plans to integrate staking and tokenized finance tools, using secure blockchain custody infrastructure to reshape its treasury operations and boost capital efficiency through yield generation.

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Cryptocurrency

Binance Moves $3B Daily in USDT via Tron, Dominating Global Transfers

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Binance has emerged as the undisputed leader in driving USDT liquidity on the Tron network. In fact, the crypto exchange routinely transacts between $2 billion and $3 billion in Tether daily.

This volume accounts for over 65% of all USDT transfers on Tron, far outpacing the combined activity of all other exchanges.

Binance: Key Driver of Tron-Based USDT Activity

According to the latest data shared by CryptoQuant, on average, Binance moves $1 billion more USDT on Tron each day than its competitors. This highlights its role as a central liquidity provider for global traders, institutions, and market makers.

The Tron network has become the preferred blockchain for large-scale stablecoin transactions due to its low fees and fast settlement times. This efficiency makes it especially attractive for high-frequency traders and institutions moving large volumes of USDT, particularly on Binance. As a result, Tron now serves as a critical backbone for USDT flows.

Meanwhile, Binance’s dominance in this space has broader implications for the market. Its stablecoin activity often is indicative of a shifting sentiment, as large USDT transfers point to potential capital rotation into altcoins, derivatives, or Bitcoin. This concentration of liquidity also presents both risk and opportunity, as per the crypto analytic platform.

Whales Power Tron’s USDT Boom

As for Tron, the network recently set a new record for USDT stablecoin transfers, which reached $691 billion in volume. The peak occurred in May, with a slight dip in June. Data also revealed that just 27 whale wallets were responsible for over $411 billion of May’s total, and were executed through only 491 transactions. This highlighted the outsized influence of large investors in driving on-chain liquidity.

Tron network now dominates the circulating supply and usage of USDT, far surpassing Ethereum and other networks. More than 10.5 billion transactions have taken place on Tron to date following a steady growth trajectory since 2018.

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