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Opaleye Management Inc. sells shares worth nearly $18k in Protara Therapeutics

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Opaleye Management Inc., a notable investment management firm, has recently sold shares in Protara Therapeutics, Inc. (NASDAQ:TARA), a company specializing in biological products. The transactions, which took place on July 1, 2024, involved the sale of a total of 8,288 shares of common stock at an average price of $2.1233, amounting to nearly $18,000.

The sales were carried out in multiple transactions with prices ranging from $2.1021 to $2.1611. This information comes from a recent Form 4 filing with the Securities and Exchange Commission, which details the trading activities of the company’s insiders.

The bulk of the shares, specifically 5,788 shares, were sold by Opaleye, L.P., a fund managed by Opaleye Management Inc., leaving them with a remaining interest of 2,213,474 shares. Additionally, a separately managed account under Opaleye’s portfolio management offloaded 2,500 shares, resulting in an ownership of 87,500 shares post-transaction.

The sales reflect transactions by an entity that is considered a ten percent owner of Protara Therapeutics, thus making these disclosures significant for investors monitoring insider activity. Opaleye Management, through its control of Opaleye, L.P. and the managed account, may be deemed to beneficially own the shares held by both entities.

Investors and the market at large often keep a close eye on insider trading patterns as they can provide insights into a company’s internal perspective and future prospects. The recent sales by Opaleye Management Inc. are now part of the public record and provide additional data points for those analyzing Protara Therapeutics’ stock performance and ownership structure.

In other recent news, Protara Therapeutics has been making significant strides in its various clinical trials. The company recently announced positive three-month data from its ongoing clinical studies of TARA-002 in patients with high-risk non-muscle invasive bladder cancer (NMIBC), which has prompted Oppenheimer to increase the stock price target to $30 from the previous $26. TD Cowen also maintained a positive outlook on Protara Therapeutics, reiterating a Buy rating and a $50.00 price target for the company’s stock, citing the encouraging results from the trials.

Protara Therapeutics also recently completed a $45 million private investment in public equity (PIPE) deal, attracting several prominent life science funds. This financial boost is expected to extend the company’s cash runway into 2026, providing a stable financial platform for continued development.

The company is also planning to initiate a registrational trial for IV Choline Chloride, targeting parenteral nutrition (PN) patients, in the first half of 2025. This comes after discussions with the U.S. Food and Drug Administration (FDA), expanding the drug’s potential use to a broader patient population.

Furthermore, Protara Therapeutics has announced a private placement financing deal expected to generate approximately $45 million in gross proceeds. The proceeds from this private placement, combined with existing cash reserves, are anticipated to fund operations into 2026.

These are the recent developments that have been reported about Protara Therapeutics.

InvestingPro Insights

As Protara Therapeutics, Inc. (NASDAQ:TARA) experiences insider trading activity, investors seeking a deeper understanding of the company’s financial health can turn to real-time data from InvestingPro. With a market capitalization of $43.03 million USD and a concerning price-to-earnings (P/E) ratio of -0.55, Protara’s financial landscape presents a complex picture. Further analysis shows that the stock’s price is currently at 40.08% of its 52-week high, and it closed at $2.03 USD in the previous session.

InvestingPro Tips for Protara Therapeutics highlight several critical factors that investors may want to consider. Notably, the company holds more cash than debt on its balance sheet, which is a positive sign for financial stability. Additionally, two analysts have revised their earnings upwards for the upcoming period, potentially indicating a more optimistic outlook for the company’s financial performance. However, it’s important to note that Protara is quickly burning through cash and suffers from weak gross profit margins, which could raise concerns about its long-term sustainability.

For investors interested in a comprehensive analysis, there are 13 additional InvestingPro Tips available for Protara Therapeutics, which can be accessed by visiting To deepen your investment research, consider utilizing the coupon code PRONEWS24 to get up to 10% off a yearly Pro and a yearly or biyearly Pro+ subscription, offering you an even greater array of tools and insights.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Stock Markets

Citi maintains Neutral on Terex shares, cites ESG business purchase

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On Monday, Terex Corporation (NYSE:) maintained its Neutral rating with a steady stock price target of $60.00, as announced by Citi. Terex disclosed it has signed an agreement to purchase Dover’s Environmental Solutions Group (ESG) business, which includes refuse vehicles and compaction equipment.

The deal is valued at $2 billion in gross terms, with a net purchase price of approximately $1.725 billion after accounting for the present value of roughly $275 million in tax benefits.

The net purchase price is approximately 9.6 times ESG’s projected 2024 EBITDA, with the multiple decreasing to around 8.4 times after factoring in the expected synergies of about $25 million. Terex anticipates the acquisition will be accretive to its adjusted earnings per share (EPS) by double digits in 2025. The acquisition is seen as beneficial, enhancing Terex’s business narrative and providing clear cost and revenue synergies.

Despite the premium paid over Terex’s current enterprise value to EBITDA multiple, the acquisition is considered potentially advantageous for Terex.

Success hinges on the company’s ability to realize the targeted synergies, the promised accretion to EPS, and ESG’s ability to deliver the forecasted mid-single-digit long-term compound annual growth rate (CAGR) with minimal business cyclicality. The transaction is slated for completion in the fourth quarter of 2024.

In other recent news, Terex Corporation has acquired Environmental Solutions Group (ESG) from Dover Corporation (NYSE:) in a deal valued at $2.0 billion, expanding its market reach. The acquisition, expected to close in the second half of 2024, will enhance Terex’s position in the waste and recycling sector. ESG’s integration will create a new Environmental Solutions segment within Terex, combining it with Terex’s existing Utilities business.

In other developments, Dover Corporation’s first-quarter earnings exceeded analyst estimates, with an adjusted EPS of $1.95, surpassing the expected $1.87. Revenue for the quarter also surpassed expectations, reaching $2.09 billion against the consensus estimate of $2.04 billion.

In analyst notes, Mizuho Securities has revised its outlook on Dover, raising its price target to $185 from the previous $180. The firm also revised its earnings per share estimates for Dover for 2024 and 2025, increasing them to $9.10 and $9.75, respectively. These recent developments indicate a positive outlook for Dover’s financial future.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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Stock Markets

Israeli parliament votes to label UN relief agency a terror organisation

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JERUSALEM (Reuters) – The Israeli parliament gave preliminary approval on Monday to a bill that declares the main United Nations relief organization for Palestinians a terrorist organisation and proposes to sever relations with the body.

The vote against the United Nations Relief and Works Agency for Palestinian Refugees (UNRWA) is the latest step in a Israeli push against the agency, which Israeli leaders have accused of collaborating with the Islamist movement Hamas in Gaza.

The bill was approved in a first reading and will be returned to the foreign affairs and defence committee for further deliberation, the Knesset information service said.

The bill’s sponsor, Yulia Malinovsky, was quoted as describing UNRWA as a “fifth column within Israel”.

UNRWA provides education, health and aid to millions of Palestinians in Gaza, the West Bank, Jordan, Lebanon and Syria. It has long had tense relations with Israel but relations have deteriorated sharply since the start of the war in Gaza and Israel has called repeatedly for UNRWA to be disbanded.

“It’s another attempt in a wider campaign to dismantle the agency,” UNRWA spokesperson Juliette Touma said. “Such steps are unheard of in the history of the United Nations.”

Israel has said hundreds of UNRWA staff are members of terrorist groups, including Hamas and Islamic Jihad, but has yet to provide evidence to a U.N.-appointed review.

© Reuters. FILE PHOTO: A United Nations Relief and Works Agency (UNRWA) sign lies on the ground, amid the ongoing conflict in Gaza between Israel and the Palestinian Islamist group Hamas,  at the Kerem Shalom crossing in southern Israel, May 30, 2024. REUTERS/Amir Cohen/File Photo

Several donor countries halted funding to UNRWA following the Israeli accusations but many have since reversed the decision, including Britain which said last week it would resume funding.

Both Hamas and the Palestinian Authority condemned the Israeli vote, and Hussein Al-Sheikh, a senior ally of Palestinian President Mahmoud Abbas, called on the international community to resist attempts to dissolve the agency.

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Stock Markets

Israel sends tanks back into Khan Younis area, 70 killed after new evacuation order

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By Nidal al-Mughrabi, Ari Rabinovitch and Hatem Khaled

CAIRO/JERUSALEM/GAZA (Reuters) -Israel sent tanks back into the greater Khan Younis area and at least 49 Palestinians were killed by Israeli fire, Gaza medics said on Monday, after ordering evacuations of some districts it said had been used for renewed attacks by militants.

The Palestinians were killed by tank salvoes in the town of Bani Suhaila and other towns fringing the eastern side of Khan Younis, with the area also bombarded by air, they said.

Residents of the densely built-up area of southern Gaza said the tanks advanced for more than two kilometres into Bani Suhaila, forcing residents to flee under fire.

“It is like doomsday,” one resident, who only identified himself as Abu Khaled, told Reuters via chat app. “People are fleeing under fire, many are dead and wounded on the roads.”

The Gaza health ministry said the dead included several women and children and that at least 186 other people had been injured by Israeli fire. The Gaza ministry does not distinguish between militants and civilians in its death tallies.

Around 400,000 people are living in the targeted areas and dozens of families have begun to leave their houses, Palestinian officials said, adding they were not given time to get out of harm’s way before the Israeli strikes began.

Some families fled on donkey carts, others on foot, carrying mattresses and other belongings.

The Palestinian Red Crescent Society said two of its clinics located in eastern Khan Younis had been knocked out of operation because of the new Israeli offensive.

At Khan Younis’ Nasser Hospital, some people stood outside the morgue to bid farewell to dead relatives.

“We are tired, we are tired in Gaza, every day our children are martyred, every day, every moment,” said Ahmed Sammour, who lost several relatives in bombings of eastern Khan Younis.

“No one told us to evacuate. They brought four floors crashing down on civilians… and the bodies they could reach, they brought to the refrigerator (morgue),” Sammour added.

There was no immediate Israeli comment on the strikes on the eastern side of Khan Younis, whose population initially fled their homes when Israeli tanks stormed in several months ago, before returning after they withdrew to rebuild their lives.

In nearby Deir Al-Balah, where hundreds of thousands of Palestinians are sheltering, an Israeli airstrike hit a tent used by local journalists inside Al-Aqsa Hospital, killing one of them and wounding two other people, the Hamas-run Gaza government media office said.

The new death raised the number of Palestinian journalists killed in the Israeli offensive to 163, it added.


Earlier on Monday, the Israeli military said it had issued new evacuation orders due to renewed Palestinian militant attacks, including rockets launched from the targeted areas in eastern Khan Younis. The orders did not include health institutions, Palestinians said.

The military said it was adjusting the boundaries of a designated humanitarian zone in coastal Al-Mawasi – to the west of Khan Younis – to keep the civilian population away from areas of combat with Hamas-led Palestinian militants.

The Gaza Civil Emergency Services said Israel’s new orders showed it had downsized the humanitarian-designated areas in southern and central areas, where 1.7 million people were sheltering, to 48 square km from 65 square km in the past.

The Palestinians, the United Nations and international relief agencies have said there is no safe place left in Gaza.

Health officials at Nasser Hospital in Khan Younis urged residents on Monday to donate blood because of the large number of casualties being rushed into the medical centre.

“A family, including children, were all torn to pieces while they were sleeping,” said one man who arrived at the hospital in an ambulance bearing the bodies.

Israel has vowed to eradicate Hamas after militants killed 1,200 people and took more than 250 hostages in a cross-border assault on Oct. 7, 2023, according to Israeli tallies.

© Reuters. A Palestinian woman sits on a wheelchair as she and others flee the eastern part of Khan Younis after they were ordered by Israeli army to evacuate their neighborhoods, amid Israel-Hamas conflict, in Khan Younis in the southern Gaza Strip July 22, 2024. REUTERS/Hatem Khaled

The death toll among Palestinians in Israel’s retaliatory offensive since then had reached at least 39,006 as of Monday, Gaza health authorities said.

A ceasefire effort led by Qatar and Egypt and backed by the U.S. has so far fallen short because of disagreements over terms between the combatants, who blame each other for the impasse.

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